1. Which are the cut-off values of 2D-Shear Wave Elastography (2D-SWE) liver stiffness measurements predicting different stages of liver fibrosis, considering Transient Elastography (TE) as the reference method? Sporea I, Bota S, Gradinaru-Taşcău O, Sirli R, Popescu A, Jurchiş A. Eur J Radiol. 2013 Dec 17. pii: S0720-048X(13)00654-2. doi: 10.1016/j.ejrad.2013.12.011.
=> Conclusion: "2D-SWE is a reliable method for the non-invasive evaluation of liver fibrosis, considering TE as the reference method. The accuracy of 2D-SWE measurements increased with the severity of liver fibrosis."
2. Relationship between the liver tissue shear modulus and histopathologic findings analyzed by intraoperative shear wave elastography and digital microscopically assisted morphometry in patients with hepatocellular carcinoma. Honjo M, Moriyasu F, Sugimoto K, Oshiro H, Sakamaki K, Kasuya K, Nagai T, Tsuchida A, Imai Y. J Ultrasound Med. 2014 Jan;33(1):61-71. doi: 10.7863/ultra.33.1.61.
=> Conclusion: "Fibrosis predictably affects elastographic estimation, but hepatocellular density (ie, hepatocellular nuclear areas) also alters elastographic assessment."
3. Nondiseased liver stiffness measured by shear wave elastography: a pilot study. Cha SW, Jeong WK, Kim Y, Kim MY, Kim J, Kim SY, Ryu JA, Kim TY, Sohn JH, Kim YH. J Ultrasound Med. 2014 Jan;33(1):53-60. doi: 10.7863/ultra.33.1.53.
=> Take Home Message: "The optimal liver stiffness threshold value for discriminating nondiseased liver from noncirrhotic chronic liver disease was 6.9 kPa. The sensitivity using this threshold was 94%."
4. Influence of Measurement Depth on the Stiffness Assessment of Healthy Liver with Real-Time Shear Wave Elastography. Wang CZ, Zheng J, Huang ZP, Xiao Y, Song D, Zeng J, Zheng HR, Zheng RQ. Ultrasound Med Biol. 2013 Dec 19. pii: S0301-5629(13)01114-9. doi: 10.1016/j.ultrasmedbio.2013.10.021.
=> Conclusion: "According to our results, the depth range for the most reliable liver stiffness assessment using SWE should be 3-5 cm from the probe surface and simultaneously 1-2 cm below the liver capsule."
Shear Wave Elastography for Differentiation of Benign and Malignant Thyroid Nodules: A Meta-analysis. Zhang B, Ma X, Wu N, Liu L, Liu X, Zhang J, Yang J, Niu T. J Ultrasound Med. 2013 Dec;32(12):2163-9. doi: 10.7863/ultra.32.12.2163.
=> Conclusion: "Shear wave elastography has high sensitivity and specificity in the evaluation of thyroid nodules and can potentially reduce unnecessary fine-needle aspiration biopsies."